Home / Stockholms Medicinska Biobank / Digit ratio 2D:4D and severity of COVID-19 / Fingerkvot (2D:4D) som markör för testosteronpåverkan under fosterlivet och svårighetsgrad av COVID-19 sjukdom

Collection

Digit ratio 2D:4D and severity of COVID-19 / Fingerkvot (2D:4D) som markör för testosteronpåverkan under fosterlivet och svårighetsgrad av COVID-19 sjukdom

Description: The aim of the project is to explore a potential relationship between the digit ratio 2D:4D, as a marker of prenatal testosterone, and severity of COVID-19 infection in men and women. Secondary aims are to investigate steroid, metabolic and immunological profiles in relation to severity of COVID-19. Furthermore, 2D:4D, steroid, metabolic and immunological profiles will be compared with controls. Data on the digit ratio 2D:4D, fasting serum, plasma, whole blood and urine will be collected from 200 men and women after hospitalization for COVID-19 and 200 sex- and age-matched controls.
Acronym:
Fingerkvotsstudien
Biobank:
Stockholms Medicinska Biobank
Local collection ID (within the biobank):
Bbk 2536

General information

Collection size:
100 - 1000 (as of 2021-02-01)
Type:
Disease specific Hospital Sample
Data:
Biological samples Medical records
Start date of sampling:
2020-11-01
End date of sampling:
2025-11-01
Collection preserved at least until:
2026-01-01
Ethical approval number:
2020-03816

Donor information

Diagnoses:
Laboratory-confirmed COVID-19 diagnosis; U07.1
Number of donors:
100 - 1000
Samples from deceased (autopsy):
no
Samples from minors (<18 years old):
no
Inclusion criteria: Two hundred patients (men and women), age 18-75 years, and treated for COVID-19 at the Karolinska University Hospital will be included in the study. They will be asked to participate in the study after recovery from COVID-19 in connection with discharge from the hospital or at a later follow-up visit. Two hundred healthy control subjects not experienced symptoms of COVID-19, and matched for sex, age and postcode will be recruited from the background population using SPAR (statliga personadressregistret).
Exclusion criteria: Exclusion criteria are: not understanding Swedish and not being willing to participate in the study. If they do not wish to participate in the study, it will not affect their further treatment. The study does not interfere with the diagnosis or course of treatment of patients in any way and does not involve any medical risk.

Sample information

Collection contact information
Collection head: Angelica Lindén Hirschberg
Contact person: Angelica Lindén Hirschberg
angelica.linden-hirschberg@sll.se
Biobank contact information
Stockholms Medicinska Biobank
Registration number at IVO: 914
biobankstockholm.karolinska@sll.se